Getein IL-6 Fast Test Kit is used as an aid in the inflammatory diseases.
Intended Use
The IL-6 Fast Test Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of interleukin 6 (IL-6) in human serum, plasma, whole blood, and peripheral blood samples. IL-6 is an early marker in acute inflammation and can be used as an aid in diagnosing inflammatory diseases.
About IL-6
IL-6 is a cytokine that functions in inflammation and the maturation of B cells. It is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response. This classical IL-6 response is governed by a receptor complex consisting of two membrane-bound subunits: an 80-kDa cognate Alpha-chain (IL-6R Alpha) and a 130-kDa Beta-chain receptor (gp130), which acts as the universal signal transducer for all IL-6 family cytokines.
Many different cells are capable of IL-6 synthesis, including monocytes/macrophages, fibroblasts, endothelial cells, keratinocytes, mast cells, T cells, and many tumor cell lines. IL-6 acts as a differentiation factor for B cells and an activation factor for T cells. It is a potent growth factor for various human myelomas and is active at concentrations below 10 pg/mL. IL-3 and IL-6 also show synergistic effects in the differentiation of hematopoietic progenitor cells.
Elevated IL-6 serum or plasma levels may occur in diseases such as sepsis, autoimmune diseases, lymphomas, AIDS, alcoholic liver disease, infections, or transplant rejection.
Specifications
Test Item:
IL-6
Sample:
Serum, Plasma, Whole Blood, Peripheral Blood
Detection Range:
1.5-4000.0 pg/mL
Storage Condition:
4-30℃
Method:
Immunofluorescence Assay
Test Time:
15 min
Cut-off Value:
7.0 pg/mL
Shelf Life:
24 months
Applicable Devices
- Getein 1100 Immunofluorescence Quantitative Analyzer
- Getein 1160 Immunofluorescence Quantitative Analyzer
- Getein 1180 Immunofluorescence Quantitative Analyzer
- Getein 1200 Immunofluorescence Quantitative Analyzer
- Getein 1600 Immunofluorescence Quantitative Analyzer
Clinical Applications
- As an aid in the early diagnosis of inflammation.
- As an aid in the prognosis of sepsis.
- As an aid in monitoring immune system disorders and patients with infections or transplant rejection.
- As an aid in diagnosing autoimmune diseases, lymphomas, AIDS, and alcoholic liver disease.
