Getein Cardiac Troponin I Fast Test Kit is used as an aid in the diagnosis of myocardial injury such as Acute Myocardial Infarction (AMI), Unstable Angina, Acute Myocarditis and Acute Coronary Syndrome (ACS).
Intended Use
The Cardiac Troponin I Fast Test Kit (Immunofluorescence Assay) is intended for in vitro quantitative determination of Cardiac Troponin I (cTnI) in human serum, plasma, or whole blood samples. This test is used as an aid in diagnosing myocardial injury, such as Acute Myocardial Infarction (AMI), Unstable Angina, Acute Myocarditis, and Acute Coronary Syndrome (ACS).
About cTnI
Troponin is a molecular complex bound to the thin filament (actin) of striated muscle fibers. It interacts with intracellular calcium to regulate muscle contraction by controlling the interaction of the thin filament with the thick filament (myosin). Troponin consists of three regulatory proteins:
- Troponin T: Connects the troponin complex and tropomyosin, another cardiac muscle regulatory protein.
- Troponin I: Prevents muscle contraction in the absence of calcium.
- Troponin C: Binds calcium.
Cardiac Troponin I (MW 22.5 kDa) and the two skeletal muscle isoforms of Troponin I have considerable amino acid sequence homology, but cTnI contains an additional N-terminal sequence and is highly specific for the myocardium. Due to its high myocardial specificity and the long duration of elevation, cTnI has become an important marker in diagnosing and evaluating patients suspected of having an acute myocardial infarction (AMI).
Specifications
Test Item:
Cardiac Troponin I (cTnI)
Sample:
Serum, Plasma, Whole Blood
Method:
Immunofluorescence Assay
Storage Condition:
4-30℃
Detection Range:
0.10~50.00 ng/mL
Test Time:
10 min
Cut-off Value:
0.10 ng/mL
Shelf Life:
24 months
Applicable Devices
- Getein 1100 Immunofluorescence Quantitative Analyzer
- Getein 1160 Immunofluorescence Quantitative Analyzer
- Getein 1180 Immunofluorescence Quantitative Analyzer
- Getein 1200 Immunofluorescence Quantitative Analyzer
- Getein 1600 Immunofluorescence Quantitative Analyzer
- Getein 208 Hand-held Integrated System
Clinical Application
- Aid in the early diagnosis of acute myocardial infarction (AMI).
- Aid in diagnosing acute myocarditis, unstable angina, and acute coronary syndrome (ACS).
- Evaluate the severity of myocardial damage.
- Aid in the prognosis of ACS.
